Blood dialysis: General heparination Before dialysis, 1,000-5,000 u; after dialysis, 1,000-1,500 u/hr continuously or intermittently. Local heparination 1,500-2,500 u/hr continuously. Blood perfusion by heart-lung machine 150-300 u/kg. Continuous IV therapy 1,000-3,000 u. Intermittent IV therapy 10,000 u then 5,000-10,000 u 4-6 hrly. SC therapy Initially 10,000-20,000 u or 8,000-10,000 u 8 hrly or 15,000-20,000 u 12 hrly. Anticoagulation in blood transfusions & blood samples 400-500 u.
Administer very slowly. Monitor thrombocyte count. Patients w/ increased risk of haemorrhage. Impaired renal function, haemorrhage after use of this drug, consumption coagulopathy, catarrh-inserted patients. Pregnancy (late trimester).
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